Anti-melanogenic effects of epigallocatechin-3-gallate (EGCG), epicatechin-3-gallate (ECG) and gallocatechin-3-gallate (GCG) via down-regulation of cAMP/CREB …
X Zhang, J Li, Y Li, Z Liu, Y Lin, J Huang - Fitoterapia, 2020 - Elsevier
Tea catechins, the main bioactive polyphenols in green tea, are well known for their health
promoting effects. Previous studies have shown that gallocatechin-3-gallate (GCG),
epigallocatechin-3-gallate (EGCG) and epicatechin-3-gallate (ECG) exerted strong
inhibitory effects on mushroom tyrosinase activity in vitro, whilst EGCG inhibited
melanogenesis in vivo, yet the underlying mechanisms are not entirely clear. In this study,
we (i) evaluated and compared the inhibitory effects of the main tea catechins (GCG, EGCG …
promoting effects. Previous studies have shown that gallocatechin-3-gallate (GCG),
epigallocatechin-3-gallate (EGCG) and epicatechin-3-gallate (ECG) exerted strong
inhibitory effects on mushroom tyrosinase activity in vitro, whilst EGCG inhibited
melanogenesis in vivo, yet the underlying mechanisms are not entirely clear. In this study,
we (i) evaluated and compared the inhibitory effects of the main tea catechins (GCG, EGCG …
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